CRISPR/Cas9 technology targeted exon 15 and generated an 8 bp deletion that causes a frameshift and premature translation termination, mimicking the human loss-of-function mutations in patients with schizophrenia. (J:328716)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count