The transgenic construct contains the 3.7 kb human SFTPC (surfactant associated protein C) promoter, the 1.3 kb human SFTPA1 (surfactant associated protein A1) variant 6A2 coding sequence containing the 5'; and 3' UTR and the entire coding region followed by an SV40 polyA signal. Founder line T1 was established. (J:161087)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count