A loxP site was inserted upstream of exon 2 and an FRT-flanked PGK-Neo cassette and second loxP site were inserted downstream of exon 3. The selection cassette was removed via flp-mediated recombination, leaving exons 2 and 3 floxed. (J:329969)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count