Log In|Sign Up
EN
The transgenic construct contains the entire human SERPINA1 gene under its endogenous promoters (both hepatocyte and macrophage) plus 5 kB of the 5' and 3 kb of the 3' flanking genomic DNA sequences. Founder line 1 carries 4 copies of the transgene. (J:329417)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
