The pituitary-specific Pomc enhancer/promoter-containing sequence 480 bp upstream of the transcription start site, including the -34 to +63 bp minimal promoter, is used to drive expression of the beta-galactosidase reporter gene. Expression of the transgene is directed to both anterior lobe corticotropes and intermediary lobe melanotropes. (J:329224)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x C3H
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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