The conserved region was targeted with crRNAs (targeting AAGAAAAGGGCCCCGCGGCCCGG and TGTAGCCAGAACACTGCCGGGGG), tracrRNA and an ssODN template (ACCCTCCCGCTGCTCTCCTGGTAGACCTAACCCTTCGCCTAATCCGCGCTGGAGATCTACCCAGTGACACTGCGGGTGTCCCCCCGGGCCCGGCAGTGTTCTGGCTACACCTGCCTTGGGGAAAACTGGCTGGAGCCGGGCGCTGGCGCCAAGACCTCTTGGGGAAATAGGAAGGCTGAA) using CRISPR/Cas9 technology, leading to a 126 bp deletion. (J:328045)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count