A loxP site was inserted upstream of exon 8 and an frt-flanked PGK-neo cassette and second loxP site were inserted downstream of exon 8. The neomycin selection cassette was removed via flp-mediated recombination. (J:328115)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count