Using CRISPR-targeting technology, the 86 kb DNA sequence containing the EC1 and EC2 (Enhancer of HoxC cluster 1 and 2) located 165 and 81 kb upstream of the HoxC cluster, respectively, was inverted. (J:297683)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x CBA)F1
Endonuclease-mediated
Inversion
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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