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The targeting cassette is composed of an FRT site, lacZ sequence, a loxP site, a neomycin resistance gene, a second FRT site, and a second loxP site inserted upstream of exon 4. A third loxP site is inserted downstream of exon 4. FLP-mediated recombination removed the lacZ and neo cassette. Cre-mediated recombination removed exon 4. (J:327825)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
