A loxP site was inserted upstream of the first exon and an FRT-flanked neomycin cassette with a 3 loxP site was inserted downstream of exon 1. Flp-mediated recombination removed the neomycin cassette leaving exon 1 floxed. (J:327404)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count