This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTACTATTCAGCAGTGTTGT and ATATGTCTGCCAATGACCTA, which resulted in a 1214 bp deletion beginning at Chromosome 19 position 60,220,288 bp and ending after 60,221,501 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001073564, ENSMUSE00000459773,and ENSMUSE00000511602 (exons 2, 3 and 4) and 844 bp of intronic sequence including the splice acceptor, start site and donor and is predicted to result in a null allele. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count