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CRISPR/cas9 genome editing is used to delete sequences incorporating the noncoding GC box sequence (GGGCGG). The GC box sequences possess enhancer activity. mRNA expression is reduced in mast cells, basophils, brain cells, and stomach cells. (J:341581)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
