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The transgene insert contains the following elements: a mutated Six1 enhancer Rr238, HSV tk gene promoter, an artificial intron, lacZ beta-galactosidase reporter gene and pol(A) signal sequences. The Rr238 mutation involves mutations to disable homeodomain (HD) protein-binding sites 1, 2 and 3. (J:163874)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
