A PGK-neo flanked by FRT sites and a loxP site were inserted in intron 1 and a second loxP site was inserted into the 5 UTR. The selection cassette was removed via flp-mediated recombination leaving exon 1 floxed. (J:235591)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count