Flp-mediated excision of the parental Ddx41tm1a(KOMP)Wtsi allele resulted in the removal of the lacZ and promoter-driven neomycin selection cassette leaving the critical exons 7-9 flanked by loxP sites. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:326963)