A loxP site and an FRT-flanked neomycin cassette were inserted upstream of exon 3 and a second loxP site was inserted downstream of exon 6. The neomycin selection cassette was removed via flp-mediated recombination leaving exons 3-6 floxed. (J:253620)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count