The targeting vector inserted into intron 3 an FRT-flanked neomycin resistance cassette with a 3' UTR and into intron 4 an additional loxP site. Flp-mediated recombination removed the selection cassette and left exon 4 floxed. (J:324714)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count