The targeting mutation inserted between exon 2 and 3 a floxed IRES-betageo cassette and into the 3' UTR an additional loxP site. Cre-mediated recombination removed the beta-geo cassette. (J:324774)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count