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This allele was created in cells containing the Gt(ROSA)26Sortm11(flpo)Amc RMCE allele. The exchange vector used contains the following elements to replace the sequence between the F3 and FRT sites in the RMCE allele: an F3 site, a neomycin resistance gene cassette minus promoter and ATG translation start site, three poly(A) signal sequences, chicken beta-globin locus insulator sequence, Nkx2-2 enhancer Rr209 (450 bp XbaI-SalI fragment), the hsp68 promoter, the lacZ beta-galactosidase reporter gene, poly(A) signal sequence and an FRT site. (J:327127)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
