In this transgene a 562 bp sequence from intron 2 of the Tbx5 gene, containing six Hox-binding sites, that is sufficient and necessary to drive forelimb expression of Tbx5, was placed upstream of a chicken beta-globin minimal promoter, the lacZ beta-galactosidase reporter gene and SV40 poly(A) signal sequences. (J:317819)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count