In this transgene a 562 bp sequence from intron 2 of the Tbx5 gene, containing six Hox-binding sites, that is sufficient and necessary to drive forelimb expression of Tbx5, was placed upstream of a chicken beta-globin minimal promoter, the lacZ beta-galactosidase reporter gene and SV40 poly(A) signal sequences. (J:317819)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
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Insertion
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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