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This allele was created using the FLEx switch system. A loxP site was inserted upstream of exon 10, a lox511 site, inverted exon 10 containing a glycine to arginine substitution at amino acid 315 (G315R), an FRT flanked neomycin selection cassette, loxP site in reverse orientation, and a lox511 site in reverse orientation were inserted downstream of exon 10. The neomycin cassette was removed via flp-mediated recombination. (J:325948)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
