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The targeting construct inserted an FRT-flanked neomycin resistance cassette downstream of exon 4 and a modified exon 5 with the mutation that corresponds to the amino acid substitution of tyrosine with phenylalanine at position 211 (Y211F). Flp-mediated recombination removed the selection cassette. (J:311101, J:325280)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
