The transgene contains a chicken beta actin (ACTB) promoter driving ubiquitous expression of a floxed lacZ neomycin reporter cassette with a triple stop, Fgf10 cDNA, IRES, and EGFP reporter gene. Cre-mediated recombination is required to remove the beta-geo cassette and achieve expression of Fgf10 and EGFP. (J:311931)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count