An A-to-G mutation was engineered in this Tbx3 enhancer using sgRNAs (targeting GGCAAGCCAGAGAAACGGGAAGG and GGGAGGTCAGTCATAATTGGCGG) and an ssODN template (GCGTCTGGGAGGTCAGTCGTAATTGGCGGAAGTTT) with CRISPR/Cas9 technology. (J:320102)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count