A loxP site and frt-flanked puromycin resistance gene cassette were inserted upstream of exon 4 and a second loxP site was inserted downstream of exon 4. The puromycin resistance cassette was removed via flp-mediated recombination leaving exon 4 floxed. (J:326714)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count