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BAC clone RP24-158J12 carrying mouse Slc6a3 (also carrying Lpcat1 (short isoform) and Clptm1l) was modified with a mammalianized tTA-Sv40 polyA signal introduced into the translation initiation site. The transgenic insertion site is unknown, but qPCR suggests that two copies of the BAC were integrated in the genome. A residual FRT and loxP site remain in the 3' end of the modified Slc6a3 segment. Founder line 2 carries higher transgene penetrance in dopamine neurons. (J:326690)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
