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CRISPR/cas9 genome editing uses two guide RNAs (uORF1 sgRNA: 5'- CCGGCGGGAATTTTTCAAAA-3' and uORF2 sgRNA: 5'- GCGTAGAGAAGGCGTCCTGA-3') and a single-stranded DNA repair template to insert the desired modification (ATG start codons of uORF1 and uORF2 were changed to ATA). (J:326689)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
