The targeting construct modified exon 14 to include the sequence coding for the amino acid substitution of asparagine with isoleucine at position 141 (N141I). Cre-mediated recombination removed the floxed selection cassette in intron 14. (J:325409)
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The targeting construct modified exon 14 to include the sequence coding for the amino acid substitution of asparagine with isoleucine at position 141 (N141I). Cre-mediated recombination removed the floxed selection cassette in intron 14. (J:325409)