A mutated version of the chicken second heart field (SHF) NK2 homeobox 5 enhancer (cardiac activating region 3 (CAR3); nucleotides 976-3047 after transcriptional start site), where the Nkx2-5-binding consensus sequence in the BMP response element (BMPRE) was mutated from TCTGAGTG to TCTGCGAG, was used to drive the expression of the cre recombinase gene. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:192448)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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