The targeting construct introduced upstream of an FRT-flanked neomycin resistance cassette with a 5 loxP site upstream of the last codon and an additional loxP site downstream of the coding sequence. Flp-mediated recombination removed the selection cassette. (J:326377)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count