The transgenic construct contains a mouse Thy1.1 (thymocyte differentiation antigen) promoter directing expression the human CAST (calpastatin) coding sequence. Founder line 12 expressed the highest amount of CAST protein (17 fold higher than controls). (J:142368)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count