The targeting vector is designed to insert a loxP site, followed by an FRT-flanked neomycin resistance (neo) cassette upstream of exon 2, and a single loxP site downstream of exon 2. Flp-mediated recombination removed the neomycin cassette. (J:84269)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count