CRISPR/cas9 genome editing was used to insert loxP sites on either side of exon 2 and a FRT-flanked neomycin cassette. Flp-mediated recombination removed the neo cassette. Cre-mediated recombination removed exon 2. (J:322368)
Basic Information
(C57BL/6 x 129S6/SvEvTac)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count