The targeting vector is designed to insert a loxP-FRT-flanked neo selection cassette upstream of exon 7. A second single loxP site was inserted just 5' of exon 10. FLP-mediated recombination removed the neo cassette. (J:323376)
Basic Information
(C57BL/6NTac x 129S6/SvEvTac)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count