A loxP site was inserted in intron 1 and an FRT-flanked IRES-Betageo and second loxP site were inserted in intron 4. The Betageo was removed via flp-mediated recombination leaving exons 1-4 floxed. (J:313620)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count