CRISPR-targeting introduced a modified exon 9 and floxed the endogenous exon 9. Cre-mediated recombination of the endogenous exon 9 will allow for expression of the 205 transcript but not the 203 transcript. (J:293217)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count