CRISPR-targeting replaced the endogenous sequence for the extracellular domain within exons 2 and 3 with the corresponding sequence from the human gene producing a fusion protein. (J:293217)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count