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CRISPR-targeting inserted the tetracycline response element driving inducible expression of the E. coli tRNA adenosine deaminase with the mutation encoding the amino acid substitution of valine with tryptophan at position 106 (V106W) fused with cas9 endonuclease. The insertion also carries a cassette composed of a CAG promoter and reverse tetracycline transactivator. (J:293217)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
