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CRISPR-targeting inserted a tetracycline response element driving inducible expression of a recombinant APOBEC1 (W90Y, R126E) fused with a cas( containing the amino acid substitution of aspartic acid with alanine at position 10 (D10A). The insertion also contains a CAG promoter dirving ubiquitous expression of a reverse tetracycline transactivator. (J:293217)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
