H2-Ab1^g7-em4Smoc

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1 H2-AA H2-Eb1 H2-Eb2 H2-Ea-ps knockout mouse models.Also, B2m gene was knocked out. These MHC class I and II molecule-deficient mice were on the M-NSG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins and B2m of class I. (J:238766)