These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Fen1 gene followed by 3xHA-IRES-EGFP tag coexpression cassette. The targeted mutation was inserted into the Rosa26 locus by homologous recombination. (J:238766)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count