These mice carry loxP sites flanking exon 2. Additionally, an FRT-flanked neomycin resistance gene was inserted downstream of the floxed exon 2. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene. (J:238766, J:307574)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count