Cd40lg^tm1.1Lorc

Using BAC RP23-153G22, a 178 bp sequence (CCCTCCCTCTCTCCCATCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCACACACACACACACACACACAGACATACACACACACACACACACACACACAGACACACACACACACACACACACACACACACACACGGAGTCAGGCTATTGTTGGCTGGT), containing most of the tandem repeats in the B and C sites of the 3' UTR stability element, was deleted. The loxP flanked neomycin resistance gene cassette that was inserted downstream of the gene was removed through subsequent cre-mediated recombination. (J:320462)