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The transgene insert consists of a segment of mouse BAC RP23-247I11 that contains the 3' half of the immunoglobulin lambda locus (from upstream of the Iglv1 promoter to 3 kb downstream of DNAse 1 hypersensitive site HS4, which is located ~40 kb downstream of the Iglj1/Iglc1 cluster). Sequence (39 bp) coding for a cMyc tag was inserted into an XhoI restriction site in the Iglc1 cluster. Further, DNAse 1 hypersensitive site HS1 was deleted (564 bp). (J:320616)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
