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A loxP site was inserted into intron 1 (185 bp downstream of the ATG start codon) and a loxP-flanked neomycin cassette was inserted into intron 2. Cre-mediated recombination removed the neomycin cassette generating a conditional allele. The coding sequence is disrupted by two short introns (1 and 2) and it is this middle intron that is floxed. (J:324922)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
