Log In|Sign Up
EN
Glutamine codon 165 (CAA) in exon 5 was changed to a stop codon (p.Q165*) and a loxP site flanked neomycin resistance gene was inserted into intron 4. The neo cassette was removed through subsequent cre-mediated recombination. The equivalent human mutation is associated with frontotemporal lobar degeneration (FTLD). (J:308471)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
