CRISPR/Cas9 technology inserted a 3' loxP site into intron 1 and a 5' loxP site 2 kb upstream of exon 1, where the promoter of the gene is located. (J:324615)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count