The promoter drives oocyte-specifiec expression of an EGFP reporter gene and a double strand RNA targeting Ctcf. Five lines were generated; lines 1 and 21 with very little CTCF mRNA while lines 4 and 56 exhibit a more modest decrease. Line 1 was selected as the representative line. (J:90538)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x SJL/J)F1
--
Insertion
--
--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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