Log In|Sign Up
EN
A G-to-A mutation was introduced in exon 4 to change arginine codon 172 (AGG) to lysine (AAG) (p.R172K) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 5. This mutation is associated with myeloid and lymphoid malignancies when found in conjunction with mutations in other genes. (J:322711)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
