This knockin is a gene editing reporter with a Venus sequence interrupted by the insertion of a 47bp sgRNA sequence that replaces 9bp of sequence (GAGCGCACC, encoding Glu, Arg and Thr), followed by Katushka2S encoded in the +2 frame such that Venus expression indicates HDR and Katushka2S expression indicates NHEJ. (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J-Gt(ROSA)26Sorem7Mvw/Mvw
Endonuclease-mediated
Insertion
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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